Yolanda Foster, 51, and David Foster, 66, announced their split in a joint statement on Tuesday.
"Sadly we have decided to go our separate ways," the couple told Us Weekly .
"We've shared 9 beautiful and joyous years together. During that time we experienced love, friendship and the inevitable challenges that come with managing a marriage, careers, blended families and health issues."
According to one insider, David's lack of support during her illness is to blame.
“She just felt he wasn’t there for him when she needed him most and he felt the same. It’s so sad but the illness really did come between them,” they revealed.
Yolanda has been battling Lyme disease after being diagnosed with the illness three years ago.
In a sneak peek of The Real Housewives of Beverly Hills series 6 , Yolanda says to camera: "I look quite normal, but yet I’m so sick. I have weakness in my legs, no brain function — I mean, I haven’t driven a car in three years.”
The ARENA star has been all over the world looking for a cure, which has been well documented on her Instagram page.
Yolanda and David married in 2011. Yolanda was previously married to Mohamed Hadid from 1994 to 2000, whom she shares 3 kids with - Gigi, Bella & Anwar Hadid.
Fans can catch the drama unfold on The Real Housewives of Beverly Hills Season 6 which starts on the 2nd December, Wednesdays 8:30pm