The director weds Jacqui Ainsley alongside celebrity pals David Beckham and Brad Pitt.
The 46-year-old Snatch director has wed his 33-year-old model girlfriend at their country home in Wiltshire, England.
The celebrity couple had been engaged for more than two-and-a-half years.
Guy shares three children with Jacqui - son Rafael, 3, and daughters Rivka, 2, and Levi, 1. Guy's other two children - Rocco, 14, and David, 9, through his previous marriage to Madonna, 56, were also in attendance.
The event was a star-studded sight with A-listers Brad Pitt, Jason Statham, Rosie Huntington-Whiteley, David Beckham and Henry Cavill in attendance.
David, 40, posted this cute tribute on Instagram:
What a beautiful day today is going to be... I want to wish my mate and his beautiful bride an amazing day where friends and family come together to celebrate what they have and are going to create together over the years to come... Have an amazing day you two... Oh and by the way don't miss Man from U.N.C.L.E .. Proud to have played a small part ... @guyritchie