Hollywood is not taking an insult to its queen very kindly, sorry Mr Trump.
"Disrespect invites disrespect. Violence incites violence. When the powerful use their position to bully others, we all lose," she told the adoring crowd of A-Listers.
In particular, Meryl focused on an incident in which Donald Trump mocked a disabled reporter.
As expected, Trump didn't take Meryl's comments lightly, preferring his belief that the three-time Oscar winner (and 19-time nominee) is 'overrated'.
Meryl Streep, one of the most over-rated actresses in Hollywood, doesn't know me but attacked last night at the Golden Globes. She is a.....— Donald J. Trump (@realDonaldTrump) January 9, 2017
Now, we don't know a whole lot about the US political system - even less after it elected Trump to its highest seat - but we do know that if Meryl Streep is anything, it's certainly NOT overrated.
Inspiring, maybe. Talented, certainly. One of the most brilliant artists of a generation, pretty much. But overrated? Oh, HELL NO.
Meryl's famous pals similarly thought calling Meryl "overrated" was pretty laughable at best, and, at worst, a total disgrace from an incumbent President. Here are some of the A-list retorts so far:
Ben Affleck put it best when he told Jimmy Kimmel: "If there's one thing truly in the world that we know is not true, it's that Meryl Streep is overrated."
In an interview with The Guardian, George Clooney responded: "Aren't you supposed to be running the country?"
"I didn't vote for him, I don't support him, I don't think he's the right choice."
"Meryl Streep is actually one of the only people on earth who is neither under or over rated. She's been 100% correctly rated!" the Girls creator wrote on Twitter.
Meryl Streep is actually one of the only people on earth who is neither under or over rated. She's been 100% correctly rated!— Lena Dunham (@lenadunham) January 10, 2017
The Star Trek actor Tweeted a picture of Meryl and the Wikipedia page dedicated solely to listing her awards and nominations.
"Overrated." -- D. Trump pic.twitter.com/JAIlGUoGGf— George Takei (@GeorgeTakei) January 10, 2017
Fellow high-achiever and one of the most successful authors in history, Stephen King, also stepped in to defend Meryl. He called Trump "childish" and "emotionally unqualified" for the US Presidency.
Trump's response to Meryl Streep--childish, churlish, petulant--is exactly why most Americans fear his presidency. Emtoionally unqualified.— Stephen King (@StephenKing) January 9, 2017
Babs went all out in defending Meryl and praising her "beautiful" speech.
“I thought that she said what she said beautifully,” Barbara said on Hardball with Chris Matthews.
“And I completely agree with Meryl - it was a heartbreaking moment and so beneath the dignity of the presidency, let alone any respectful person. And what we need more in this world is kindness and common decency, and how he reacts and how he has the need to talk back and insult anybody who doesn’t agree with him, that’s pretty disgraceful.
"Why isn’t he sitting through briefings rather than tweeting this nonsense? I don’t know how we’re going to take four years of this,” she said before returning to her teeth cleaning.”